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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA5 All Species: 23.33
Human Site: S923 Identified Species: 51.33
UniProt: Q8WWZ7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WWZ7 NP_061142.2 1642 186508 S923 L L Q N S A D S D I S D L I S
Chimpanzee Pan troglodytes XP_511650 1642 186524 S923 L L Q N S T D S D I S D L I S
Rhesus Macaque Macaca mulatta XP_001082244 1618 183230 A923 L I I N K T G A S I D D F I H
Dog Lupus familis XP_537573 1642 186609 S923 L L Q N S T D S D I S D L I S
Cat Felis silvestris
Mouse Mus musculus Q8K448 1642 185876 S923 L L Q N S T D S D I N G L I E
Rat Rattus norvegicus Q8CF82 1642 185792 S923 L L Q N S T D S D I N D L I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509469 1722 195635 S1003 L L Q N S T D S D I D D L I S
Chicken Gallus gallus XP_415695 1646 186355 I928 Q N S T D S D I D D V V R S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092716 1654 185619 S925 L V Q N S T D S D L S G F I H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 K1024 E E A A N F E K I L R K S G G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 P1077 D A I D A A G P T L G P T L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 42.1 93 N.A. 90 90.2 N.A. 81.3 71.5 N.A. 52 N.A. N.A. N.A. 22.5 N.A.
Protein Similarity: 100 99.8 62.8 96.7 N.A. 94.8 95.1 N.A. 88 86 N.A. 70.5 N.A. N.A. N.A. 44.1 N.A.
P-Site Identity: 100 93.3 33.3 93.3 N.A. 73.3 80 N.A. 86.6 13.3 N.A. 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 93.3 46.6 93.3 N.A. 80 86.6 N.A. 86.6 20 N.A. 73.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 10 19 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 10 0 73 0 73 10 19 55 0 0 10 % D
% Glu: 10 10 0 0 0 0 10 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 19 0 0 % F
% Gly: 0 0 0 0 0 0 19 0 0 0 10 19 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % H
% Ile: 0 10 19 0 0 0 0 10 10 64 0 0 0 73 0 % I
% Lys: 0 0 0 0 10 0 0 10 0 0 0 10 0 0 0 % K
% Leu: 73 55 0 0 0 0 0 0 0 28 0 0 55 10 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 73 10 0 0 0 0 0 19 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % P
% Gln: 10 0 64 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % R
% Ser: 0 0 10 0 64 10 0 64 10 0 37 0 10 10 37 % S
% Thr: 0 0 0 10 0 64 0 0 10 0 0 0 10 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _